Preacting subthreshold outward ionic current and its contribution into the dynamics of nerve impulse propagation
1422901 pp. (accepted)
There is an opinion that the leading edge of a traveling wave (for example, a nerve impulse) is formed by inward ionic current through membrane and this current defines the velocity of the leading edge and thus impulse propagation velocity. This is the main point Markin-Chizmadzhev research essay that allows to calculate it analytically.
But this opinion is only partly true. Thorough analysis of wave propagation physical mechanism predicts the existence of under threshold low amplitude outward ionic current that precedes inward threshold ionic current. In this work we confirm this with numerical experiments using classical Hodgkin-Huxley equation.