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Abstracts

XXIV conference

Investigation of the causes of glaucoma. Mathematical modeling hydrodynamic outflow fluid through the Schlemm's canal

Skladchikov S.A., Savenkova N.P., Novoderegkin V.V.1

Moscow state university, department of calculational mathematics and cybernetics.

1City clinical hospital №15, Moscow.

1 pp. (accepted)

It is known that 90% of outflow intraocular fluid is precisely through the trabecular meshwork. The degree depends on the amount of outflow intraocular pressure and increases with increasing it. Intraocular fluid passes through the trabecular meshwork into Schlemm's canal and from there flows off in the vein system. Inner pressure higher than the pressure in the episcleral veins P * (8 - 15 mm Hg). If the intraocular pressure is lower than the pressure P *, the outflow has to go on uveskleralnomu way, ie through the surface of the ciliary body, through the iris root and then to the perivascular space. Schlemm's canal is a tube with a diameter of 190 - 350 m Located at the base of the groove and scleral vodenistuyu collects moisture which then enters the venous system. With high eye pressure Schlemm's canal is composed, with the sharp increase in the outflow of intraocular fluid resistance.

This work describes reasons of grouth intraocular pressure due to outflow fluid deterioration, which may lead to evolution of pathologies (glaucoma, cataracts, etc.). In this work we describe three-dimensional mathematical model of fluid flow in the anterior chamber of the eye, according the actual geometry. The fluid in the anterior chamber goes through the gap between the lens and the iris. The outflow occurs from the anterior chamber angle in Schlemm's canal. The effect of location Schlemm's Canal in the quality of the outflow fluid from the eye is investigated.



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