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Conference publicationsAbstractsXX conferenceBiophysics as living systems theoryFaculty Natural Sciences, dept. Neurobiology and Biophysics, Lithuania, LT-03101, Vilnius, M.K.Čiurlionio 21/27, Tel.: +370-5-2398225, fax.: +370-5-2398204, E-mail: dobilas.kirvelis@gf.vu.lt 1 pp. (accepted)Today biophysics is not only molecular or physico-chemical cell biology, but according to Aristotle's conception of physics, has become a fundamental bio-theory of the life, living nature or living systems. Aristotle explained physics as living and non-living nature. Non-living nature has been interpreted in dynamis/potente, energeya values (traditional physics), and for living nature interpretation (biophysics) was a necessity additional entelecheya - purposeful, goal-oriented activities as life “organizing force” (information today). The biophysics of the twenty-first century is beginning of radical changes. Biophysics is transforming to fundamental life science, arise a new biophysics paradigm, as by information organized systems of bio-technologies. The last decades of research point to a conceptual turn in biology to technology. "Conceptually at least, biology is becoming technology. And physically, technology is becoming biology" [W.B. Arthur, 2009]. Another word for this is "Wetware: a computer in every living cell" [D. Bray, 2009]. The J.G. Miller's living systems theory allege that the space and time, the matter and energy, the information and entropy are conceptual techno-engineering factors in different levels of life organization. The essence of life and living systems is their organization on the base bioinformational technology of informational control. The opinion that biological evolution of species is evolution of the natural life technologies are developed by R. Kurzweil. Schrödinger studied the basic element of life, the cell, concluded that "life feeds on negentropy" and that "the known laws of physics are not sufficient to explain life." The negentropic concept brought the idea that the living organism in a limited space can reduce its own entropy, i.e., to increase the functional organizational skills at the expense of environmental resources. It’s shows that life is organized functionally targeted technology system, is controlled by the special structure of the biological information-technologies (genetic, molecular signals, hormones, neuro-networks, pheromones, sound signals, etc.), by means of closed, cyclic (recursive) operating in the closed-loop coding-decoding (CL-CD) circuits of control systems (D. Kirvelis, 2002-2009). The CL-CD concept as genotype-phenotype approach joins information-signals and physical processes in the functionally organized - semantic procedures. The bio-infotechnologies that determine the essence of life on CL-CD functional principle is always made from the material-signal (hard) and intangible (soft) technologies. Hard-Soft concept eliminates the misunderstandings between physicists and cyberneticists on understanding of information, as well as between biologists and biochemists theorists - Vis Vitalis. The feature reducing of the entropy, which is organizational skills-enhancing properties of this system is acquired by information technology. That is essence of organized system to help fight against the second law of thermodynamics. This bio-engineering technological approach was already seen by the pioneers of bioinformatics G.Gamow, M. Yčas, biotheoreticists H. Maturana, J. Varela, and biosemiotists. Such an integrated life science that leads to the future of humanity for creation and implementation of Converging Nano-Bio-Info-Cogno-Eco (NBICE) technologies, must be basic science – BIOPHYSICS.
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